Al Fin, You Sexy Thing!

11 July 2006

News Flash: Men are Now Officially Disposable!

Feminists have long blamed all the problems of the world on men, and have maintained that the only reason men are allowed to continue existing is the need for sperm to propagate the species. Now, thanks to scientists in Germany and England, sperm can be created in the lab, using embryonic stem cells.

Scientists have demonstrated for the first time that embryonic stem (ES) cells cultured in the laboratory can produce sperm with the capacity to produce viable offspring. The research, published in the July issue of Developmental Cell, opens many exciting avenues for future studies, including investigation of mechanisms involved in sperm production and development of new treatment strategies for infertility.

Previous studies have shown that ES cells grown in the laboratory can differentiate into primordial germ cells that then give rise to cells resembling mature egg and sperm cells, known as gametes. However, the functionality of the gametes has not been thoroughly tested and many questions about the viability of these cells remain unanswered. Dr. Karim Nayernia and Dr. Wolfgang Engel from the Institute of Human Genetics at the University of Goettingen in Goettingen, Germany and colleagues developed a new strategy for generating mature sperm cells in the laboratory using ES cells from mice and went on to test the functionality of the ES-derived sperm.

ES cells were treated with specific factors know to direct sperm production and screened for characteristics associated with primordial and spermatagonial stem cells. The researchers demonstrated that these cells could be further differentiated into mature sperm in the laboratory or could be transplanted into the testes of mice where they retained the capacity develop into sperm. Intra-cytoplasmic injection of the ES-derived sperm into mouse eggs resulted in successful fertilization and the resulting early stage embryos were successfully transplanted into mice. Six of the seven mice born developed into adult mice.

The results of this study establish that the ES cell derived cell lines can produce functional sperm in the laboratory which can be used to successfully fertilize eggs and support full-term development into embryos and adult mice.

Abstract from original article from Cell.

Men are no longer necessary to propagate the species. Sperm cells are necessary, but mean are no longer needed to produce sperm. This is where feminist fantasies come into the realm of realistic scenarios.

It is likely that eggs can also be generated through similar technologies, but that would not mean the end of the need for women for human propagation. The female womb is still the only proven incubator for the developing human, other than a small number of documented abdominal pregnancies.

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