Al Fin, You Sexy Thing!

04 August 2006

More Ongoing Research on PT-141, Bremelanotide

Bremelanotide (Palatin Tech Amex PTN) is an agonist for the melanocortin 4 receptor (MC4R) in the brain. As it happens, the MC4R also affects energy balance, thus weight levels. To complete the hat trick for PT-141, as an alpha MSH analog, Bremelanotide (PT-141) also the MC1R which affects pigmentation levels. Put it all together, and you have slender, well-tanned, and very horny people, ready to frolic in the sun, as well as in places where the sun does not shine!

Here is more information with scientific references from The Neurocritic Blog:

A good place to start if you really want to learn about MC4-R agonists is this article:

Nargund RP, Strack AM, Fong TM. (2006). Melanocortin-4 receptor (MC4R) agonists for the treatment of obesity. J Med Chem. 49:4035-43.

....Funniest lines from the article:

If MC4R agonists induce spontaneous penile erections in men, this would represent a significant impediment to the development of compounds to treat obesity.

....Is PT-141 really a miracle drug? That's highly doubtful. But, as PZ Myers said,

Wow. Makes me want to run out and buy stock in Palatin Technologies, the manufacturer.
More scientific references at the source.

As this article reports, research on Bremelanotide is progressing quickly. To this point, safety and efficacy studies look good, for the indication of erectile dysfunction. But we all really know that ED is not what PT-141 is all about. PT-141 is about sexual desire and pleasure for both men and women, whenever they want it.

If weight loss and a good tan come along with the heightened libido, who's going to complain?

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